Modular synthesis of 2-furyl carbinols from 3-benzyldimethylsilylfurfural platforms relying on oxygen-assisted C–Si bond functionalization

• Sebastien Curpanen,
• Per Reichert,
• Gabriele Lupidi,
• Giovanni Poli,
• Julie Oble and
• Alejandro Perez-Luna

Beilstein J. Org. Chem. 2022, 18, 1256–1263, doi:10.3762/bjoc.18.131

• carbinols from renewable feedstock. Keywords: biomass; copper; cyclic siloxanes; 2-furyl carbinols; silicon; Introduction Progress towards the use of nonedible renewable feedstock to replace fossil resources as starting material for high-value chemicals is an important endeavor of modern synthesis [1][2

Synthesis of a tyrosinase inhibitor by consecutive ethenolysis and cross-metathesis of crude cashew nutshell liquid

• Jacqueline Pollini,
• Valentina Bragoni and
• Lukas J. Gooßen

Beilstein J. Org. Chem. 2018, 14, 2737–2744, doi:10.3762/bjoc.14.252

• subsequent hydrogenation step. Overall, the target compound was obtained in an overall yield of 61% based on the unsaturated anacardic acid content and 34% based on the crude CNSL. Keywords: cashew nutshell liquid; cross-metathesis; renewable feedstock; sustainable chemistry; tyrosinase inhibitor

• ; Introduction Cashew nutshell liquid (Scheme 1) is an ideal renewable feedstock. This non-edible industrial waste product, derived from the cashew nut processing, is abundant available and cheap [1][2][3]. The annual production of cashew nuts with shell reached 4.9 million tons in 2016 [4], leading to an

Cobalt- and rhodium-catalyzed carboxylation using carbon dioxide as the C1 source

• Tetsuaki Fujihara and
• Yasushi Tsuji

Beilstein J. Org. Chem. 2018, 14, 2435–2460, doi:10.3762/bjoc.14.221

• [2 + 2 + 2] cycloaddition of diynes and CO2 proceeds to afford pyrones. Keywords: carbon dioxide; carboxylation; cobalt; homogeneous catalysts; rhodium; Introduction Carbon dioxide (CO2) is one of the most important materials as renewable feedstock [1][2][3][4]. However, the thermodynamic and

Sustainable synthesis of 3-substituted phthalides via a catalytic one-pot cascade strategy from 2-formylbenzoic acid with β-keto acids in glycerol

• Lina Jia and
• Fuzhong Han

Beilstein J. Org. Chem. 2017, 13, 1425–1429, doi:10.3762/bjoc.13.139

• efficient one-pot cascade aldol/cyclization methodology using the low-cost and renewable feedstock glycerol as the solvent. A broad substrate scope for β-keto acids is strongly compatible with this catalytic process, affording a wide variety of 3-substituted phthalides in good to excellent yields. Further

Diels–Alder reactions of myrcene using intensified continuous-flow reactors

• Christian H. Hornung,
• Miguel Á. Álvarez-Diéguez,
• Thomas M. Kohl and
• John Tsanaktsidis

Beilstein J. Org. Chem. 2017, 13, 120–126, doi:10.3762/bjoc.13.15

• continuous-flow approach provides a facile alternative scale-up route to conventional batch processing, and it helps to intensify the synthesis protocol by applying higher reaction temperatures and shorter reaction times. Keywords: continuous processing; flow chemistry; renewable feedstock; surfactant

Experimental and theoretical insights in the alkene–arene intramolecular π-stacking interaction

• Valeria Corne,
• Ariel M. Sarotti,
• Carmen Ramirez de Arellano,
• Rolando A. Spanevello and
• Alejandra G. Suárez

Beilstein J. Org. Chem. 2016, 12, 1616–1623, doi:10.3762/bjoc.12.158

•  1). Saponification of adducts 11 and 12 provided the free 5-norbornenecarboxylic acid and the chiral auxiliaries 5a and 5b in excellent yields, which can be reused. Conclusion We have reported the synthesis of chiral acrylates derived from renewable feedstock as models to study arene–alkene π

Biocatalysis for the application of CO₂ as a chemical feedstock

• Apostolos Alissandratos and
• Christopher J. Easton

Beilstein J. Org. Chem. 2015, 11, 2370–2387, doi:10.3762/bjoc.11.259

• current oxidative technologies that rely on diminishing natural fossil-fuel deposits. Enzymes that catalyse CO2 fixation steps in carbon assimilation pathways are promising catalysts for the sustainable transformation of this safe and renewable feedstock into central metabolites. These may be further

Highly selective generation of vanillin by anodic degradation of lignin: a combined approach of electrochemistry and product isolation by adsorption

• Dominik Schmitt,
• Carolin Regenbrecht,
• Marius Hartmer,
• Florian Stecker and
• Siegfried R. Waldvogel

Beilstein J. Org. Chem. 2015, 11, 473–480, doi:10.3762/bjoc.11.53

• formation of vanillin (1) and a novel as well as viable work-up concept exploiting strongly basic anion exchange resins. As renewable feedstock we employed alkaline lignin solutions. Alloys of cobalt and nickel as anodic material are suitable forming in situ electrochemically active MO(OH) coatings. Despite